在小鼠局部应用14C标记的1,3-双（2-氯乙基）-1-亚硝基脲（BCNU）后14C的分布情况。
Distribution of 14C after topical application of 14C-labeled 1,3-bis-(2-chloroethyl)-1-nitrosourea (BCNU) in mice.
作者信息
Zackheim H S, Feldmann R J, Lindsay C, Maibach H I
出版信息
Experientia. 1977 Jun 15;33(6):753-4. doi: 10.1007/BF01944171.
PMID:891737
Abstract
Following topical application of 14C-labeled 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU, carmustine) to the skin of mice radioactivity was found in all viscera and tissues examined. Exclusive of the gut, highest values were recorded for the liver, kidney and lung.
摘要
将14C标记的1,3-双（2-氯乙基）-1-亚硝基脲（BCNU，卡莫司汀）局部涂抹于小鼠皮肤后，在所有检查的内脏和组织中均发现有放射性。除肠道外，肝脏、肾脏和肺的放射性值最高。
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