Nagaraj J S
Experientia. 1977 Sep 15;33(9):1186-7. doi: 10.1007/BF01922318.
The levels of gamma aminobutyric acid decreased, while glutamic acid and aspartic acid levels increased in the forebrain, and decreased in the mid and hind brain regions of frog, Rana cyanophlictis during alloxan diabetes. Since glutamic acid and GABA are intimately involved in the central nervous system (CNS) functions, the alterations occurring in their levels during alloxan diabetes may be significant in bringing about a correlation between the diabetic state and the altered functional dynamics of the CNS.
在四氧嘧啶糖尿病期间，黑斑侧褶蛙前脑中γ-氨基丁酸水平降低，而谷氨酸和天冬氨酸水平升高，中脑和后脑区域的这些氨基酸水平则降低。由于谷氨酸和γ-氨基丁酸密切参与中枢神经系统（CNS）功能，在四氧嘧啶糖尿病期间它们水平的变化可能在建立糖尿病状态与中枢神经系统功能动态改变之间的关联方面具有重要意义。
