• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Candletoxins A and B, 2 new aromatic esters of 12-deoxy-16-hydroxy-phorbol, from the irritant latex of Euphoria poisonii Pax.

作者信息

Schmidt R J, Evans F J

出版信息

Experientia. 1977 Sep 15;33(9):1197-8. doi: 10.1007/BF01922325.

DOI:10.1007/BF01922325
PMID:891875
Abstract

2 new aromatic esters of 12-deoxy-16-hydroxy-phorbol, known as candletoxins A and B, were isolated from the irritant latex of Euphorbia poisonii Pax. Compound A was identified as 12-deoxy-phorbol-13-O-phenylacetate-16-O-alpha-methyl-butyrate-20-acetate, and compound B was the C-20 desacetyl analogue.

摘要

相似文献

1
Candletoxins A and B, 2 new aromatic esters of 12-deoxy-16-hydroxy-phorbol, from the irritant latex of Euphoria poisonii Pax.
Experientia. 1977 Sep 15;33(9):1197-8. doi: 10.1007/BF01922325.
2
The succulent euphorbias of Nigeria. III. Structure and potency of the aromatic ester diterpenes of Euphorbia poissonii Pax.尼日利亚的肉质大戟属植物。III. 泊松大戟芳香酯二萜的结构与效力
Acta Pharmacol Toxicol (Copenh). 1979 Sep;45(3):181-91. doi: 10.1111/j.1600-0773.1979.tb02380.x.
3
The succulent Euphorbias of Nigeria. II. aliphatic diterpene esters of the latices of E. poisonii Pax. and E. unispina N.E. Br.
Lloydia. 1977 May-Jun;40(3):225-9.
4
Irritant contact dermatitis in humans from phorbol and related esters.佛波醇及相关酯类导致的人类刺激性接触性皮炎。
Toxicon. 1981;19(6):841-50. doi: 10.1016/0041-0101(81)90080-5.
5
The irritant toxins of Blue Euphorbia (Euphorbia coerulescens Haw).
Toxicon. 1978;16(1):51-7. doi: 10.1016/0041-0101(78)90060-0.
6
On the active principles of the spurge family (Euphorbiaceae). V. Extremely skin-irritant and moderately tumor-promoting diterpene esters from Euphorbia resinifera Berg.关于大戟科植物的活性成分。V. 来自树脂大戟的极具皮肤刺激性且有中度促肿瘤作用的二萜酯
J Cancer Res Clin Oncol. 1984;108(1):98-109. doi: 10.1007/BF00390980.
7
Skin irritants of Euphorbia fortissima.
J Pharm Pharmacol. 1975 May;27(5):329-33. doi: 10.1111/j.2042-7158.1975.tb09450.x.
8
Skin irritant effects of esters of phorbol and related polyols.
Arch Toxicol. 1980 Apr;44(4):279-89. doi: 10.1007/BF00278035.
9
Radiomimetic activity of phorbol esters exerted in HeLa cells in comparison with their tumor-promoting capacity.佛波酯在HeLa细胞中发挥的拟放射性活性与其促肿瘤能力的比较。
Cancer Res. 1984 Jan;44(1):139-43.
10
On the active principles of the spurge family. III. Skin irritant and cocarcinogenic factors from the caper spurge.关于大戟科植物的活性成分。III. 刺续断大戟中的皮肤刺激和促癌因素。
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1975 Nov 25;84(3):325-44. doi: 10.1007/BF00312253.

引用本文的文献

1
Pharmacological Significance, Medicinal Use, and Toxicity of Extracted and Isolated Compounds from Species Found in Southern Africa: A Review.从南非发现的物种中提取和分离的化合物的药理意义、药用价值及毒性：综述
Plants (Basel). 2025 Feb 5;14(3):469. doi: 10.3390/plants14030469.
2
Isolation and Identification of 12-Deoxyphorbol Esters from Berg Latex: Targeted and Biased Non-Targeted Identification of 12-Deoxyphorbol Esters by UHPLC-HRMS.从大戟乳胶中分离和鉴定12-脱氧佛波醇酯：通过超高效液相色谱-高分辨质谱对12-脱氧佛波醇酯进行靶向和偏向非靶向鉴定
Plants (Basel). 2023 Nov 14;12(22):3846. doi: 10.3390/plants12223846.
3
Skin irritant effects of esters of phorbol and related polyols.

本文引用的文献

1
[On the biologically active compounds of euphorbiaceae. I. Skinirritant and cocarcinogenic factors from Euphorbia cooperi N.E.Br (author's transl)].[关于大戟科植物的生物活性化合物。I. 库珀大戟（Euphorbia cooperi N.E.Br）中的皮肤刺激和促癌因素（作者译）]
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1973 Dec 28;80(4):335-50. doi: 10.1007/BF00284369.
2
The succulent euphorbias of Nigeria. Part I.
Lloydia. 1975 Jul-Aug;38(4):363-5.
Arch Toxicol. 1980 Apr;44(4):279-89. doi: 10.1007/BF00278035.
4
On the active principles of the spurge family (Euphorbiaceae). V. Extremely skin-irritant and moderately tumor-promoting diterpene esters from Euphorbia resinifera Berg.关于大戟科植物的活性成分。V. 来自树脂大戟的极具皮肤刺激性且有中度促肿瘤作用的二萜酯
J Cancer Res Clin Oncol. 1984;108(1):98-109. doi: 10.1007/BF00390980.
5
An assay procedure for the comparative irritancy testing of esters in the tigliane and daphnane series.
Inflammation. 1979 Jul;3(3):215-23. doi: 10.1007/BF00914178.