Dray A, Oakley N R
Experientia. 1977 Sep 15;33(9):1198-200. doi: 10.1007/BF01922326.
Methiothepin reduced both median-raphe evoked and exogenous 5-HT depression of single substantia nigra neurones. While this is compatible with a serotonin releasing pathway, additional interactions of methiothepin with exogenous dopamine suggest the need for further pharmacological confirmation.
甲硫噻平降低了中缝正中核诱发的以及外源性5-羟色胺对单个黑质神经元的抑制作用。虽然这与5-羟色胺释放途径相符,但甲硫噻平与外源性多巴胺的其他相互作用表明需要进一步的药理学证实。