Beris A E, Soucacos P N, Seaber A V, Urbaniak J R
Department of Orthopaedic Surgery, University School of Medicine, Ioannina, Greece.
Int Angiol. 1995 Sep;14(3):248-52.
In replantation and tissue transplantation an ischemic period is inevitable until blood flow is reestablished. This study evaluated the reflow patterns of the rat cremaster microcirculation after warm and cold ischemia with the use of vital microscopy. The present studies indicate that hypothermia (cold temperatures of about 5 degrees C) protects arteries from excessive spasm during ischemia and also lessens the reactive hyperemia. The enhanced reflow patterns may be attributed to decreased vessel injury and the diminution of metabolic needs of the hypothermic muscle. These results support the use of hypothermia even for short ischemic periods during microsurgery procedures in order to prevent adverse effects on the reflow patterns of the tissue.
在再植和组织移植中，在血流重建之前，缺血期是不可避免的。本研究利用活体显微镜评估了大鼠提睾肌微循环在温暖和寒冷缺血后的再灌注模式。目前的研究表明，低温（约5摄氏度的寒冷温度）可保护动脉在缺血期间免受过度痉挛，并且还可减轻反应性充血。增强的再灌注模式可能归因于血管损伤的减少以及低温肌肉代谢需求的降低。这些结果支持即使在显微外科手术的短暂缺血期也使用低温，以防止对组织的再灌注模式产生不利影响。
