Desai S, Jambhekar N
Department of Pathology, Tata Memorial Hospital, Bombay, India.
Indian J Pathol Microbiol. 1995 Jan;38(1):49-54.
This is a clinicopathological study of 114 cases of metastatic carcinomas of bone accessioned between 1979 and 1988 at a large cancer hospital. The cases were divided into two groups. The first group comprised of 68 cases (59.64 percent), which included those where the primary was either known (Ia-12 cases), detected after simple investigations (Ib - 18 cases) or detected after extensive investigations (Ic - 38 cases). The lung emerged as the primary source of the metastases in almost half the cases. Hence an X-ray chest should be the basic essential investigation in the workup of skeletal metastasis. The second group comprised of 46 cases (40.35 percent), where the primary remained unknown; 56.5 percent of these were adenocarcinomas. When the histological diagnosis is adenocarcinoma in cases of an occult primary, it is often difficult to pinpoint the primary site after exclusion of organs like breast, prostate, thyroid and kidney.
这是一项针对1979年至1988年间在一家大型癌症医院登记的114例骨转移性癌的临床病理研究。这些病例被分为两组。第一组包括68例（59.64%），其中包括原发灶已知的病例（Ia组 - 12例）、经简单检查后发现的病例（Ib组 - 18例）或经广泛检查后发现的病例（Ic组 - 38例）。在几乎一半的病例中，肺成为转移灶的主要来源。因此，胸部X线检查应是骨骼转移检查中的基本必要检查。第二组包括46例（40.35%），其原发灶仍不明；其中56.5%为腺癌。在隐匿性原发灶病例中，当组织学诊断为腺癌时，在排除乳腺、前列腺、甲状腺和肾脏等器官后，往往难以确定原发部位。
