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[实验性诱发全身性惊厥对睡眠-觉醒周期的影响]

[Effect of experimentally induced generalized convulsions on the sleep-wakefulness cycle].

作者信息

Koridze M G, Mgaloblishvili M M, Kavkasidze M G

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1977 May;63(5):617-25.

PMID:892070
Abstract

Electrical stimulation of the dorsal hippocampus appeared to have obvious effect on the ratio of phases of the wakefulness--sleep cycle: during the postconvulsive period when wakefulness is prolonged, paradoxical sleep is sharply decreased, while the slow wave sleep changes are insignificant. However, this effect is less pronounced after generalized seizures evoked by amygdaloid stimulation. Thus unspecific hyperactivation of the brain during experimentally induced generalized seizures exert an acute effect on the paradoxical sleep shortening its duration. This emphasized the functional significance of paradoxical sleep that might be a periodical increase of the brain activity during sleep.

摘要

对背侧海马体进行电刺激似乎对清醒-睡眠周期各阶段的比例有明显影响:在惊厥后阶段,清醒时间延长,异相睡眠急剧减少,而慢波睡眠变化不显著。然而,在杏仁核刺激诱发全身性癫痫发作后,这种影响不太明显。因此,在实验诱导的全身性癫痫发作期间大脑的非特异性过度激活对异相睡眠产生急性影响,缩短其持续时间。这强调了异相睡眠的功能意义,它可能是睡眠期间大脑活动的周期性增加。

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