Matwichuk C L, Taylor S M, Wilkinson A A, Dudzic E M, Matte G G, Outerbridge C A, Schmon C L, Ihle S L
Department of Veterinary Internal Medicine, Western College of Veterinary Medicine, Saskatoon, Saskatchewan, Canada.
J Am Vet Med Assoc. 1996 Nov 15;209(10):1733-6.
Double-phase parathyroid gland scintigraphy, using technetium Tc 99m sestamibi, correctly identified the existence and location of a parathyroid adenoma in a dog with primary hyperparathyroidism. The parathyroid adenoma was removed surgically 2 days after scintigraphy. An area of focal radionuclide uptake persisted in the region corresponding to the left external parathyroid gland in the delayed-phase image. Delayed-phase images from 3 healthy dogs and a dog with hypercalcemia of malignancy caused by lymphoma did not reveal an area of persistent radiotracer uptake. Double-phase parathyroid gland scintigraphy, using 99mTc-sestamibi, is a simple, rapid, noninvasive test, which can be used for detection and localization of parathyroid adenomas in hypercalcemic dogs. It also can help to differentiate these dogs from dogs with hypercalcemia of malignancy.
使用锝 Tc 99m 甲氧基异丁基异腈进行的双期甲状旁腺闪烁扫描，正确识别出一只患有原发性甲状旁腺功能亢进症的犬甲状旁腺腺瘤的存在及位置。闪烁扫描后 2 天，通过手术切除了甲状旁腺腺瘤。在延迟期图像中，对应于左外侧甲状旁腺的区域持续存在局灶性放射性核素摄取区域。3 只健康犬以及一只由淋巴瘤引起恶性肿瘤高钙血症的犬的延迟期图像未显示放射性示踪剂持续摄取区域。使用 99mTc-甲氧基异丁基异腈进行的双期甲状旁腺闪烁扫描是一种简单、快速且无创的检查方法，可用于检测和定位高钙血症犬的甲状旁腺腺瘤。它还有助于将这些犬与患有恶性肿瘤高钙血症的犬区分开来。
