Egbase P E, al-Sharhan M, al-Othman S, al-Mutawa M, Udo E E, Grudzinskas J G
IVF Centre, Maternity Hospital, Kuwait.
Hum Reprod. 1996 Aug;11(8):1687-9. doi: 10.1093/oxfordjournals.humrep.a019470.
A total of 110 consecutive women was studied prospectively at the time of transcervical embryo transfer following conventional in-vitro fertilization and intracytoplasmic sperm injection procedures. Microbiological cultures were performed on endocervical swabs and embryo transfer catheter tips. Positive microbial growths were observed from endocervical swabs in 78 (70.9%) women and from catheter tips in 54 (49.1%) women. The clinical pregnancy rates were 57.1% in the group of patients without growth and 29.6% in the group with positive microbial growth from catheter tips. As microbial contamination at embryo transfer may influence implantation rates, prospective studies are justified to determine whether eradication of endocervical micro-organisms is possible and whether their eradication will improve implantation rates.
在进行常规体外受精和卵胞浆内单精子注射程序后的经宫颈胚胎移植时，对连续110名女性进行了前瞻性研究。对宫颈内拭子和胚胎移植导管尖端进行了微生物培养。78名（70.9%）女性的宫颈内拭子以及54名（49.1%）女性的导管尖端观察到微生物生长阳性。无微生物生长的患者组临床妊娠率为57.1%，导管尖端微生物生长阳性的组为29.6%。由于胚胎移植时的微生物污染可能影响着床率，因此有必要进行前瞻性研究，以确定是否有可能根除宫颈内微生物以及根除这些微生物是否会提高着床率。
