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一种基于公共线的方法，用于同时确定N>3个粒子投影的方向。

A common-lines based method for determining orientations for N > 3 particle projections simultaneously.

作者信息

Penczek P A, Zhu J, Frank J

机构信息

Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201-0509, USA.

出版信息

Ultramicroscopy. 1996 Jul;63(3-4):205-18. doi: 10.1016/0304-3991(96)00037-x.

DOI:10.1016/0304-3991(96)00037-x
PMID:8921628
Abstract

A method is proposed for determining the directions of projections. An arbitrary number of projections of unknown three-dimensional structure are simultaneously used as input. The method is based on common lines and uses a new discrepancy measure accounting for the uneven distribution of common lines in angular space. An application to the 70S Escherichia coli ribosome data obtained from an energy-filtering electron microscope is described.

摘要

提出了一种确定投影方向的方法。任意数量的未知三维结构的投影同时用作输入。该方法基于公共线，并使用一种新的差异度量来考虑公共线在角空间中的不均匀分布。描述了该方法在从能量过滤电子显微镜获得的70S大肠杆菌核糖体数据中的应用。

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