Makarychev V A, Kashtanov S I, Starinskiĭ Iu G, Ul'ianinskiĭ L S
Kardiologiia. 1979 Jul;19(7):98-101.
The dynamics of changes in the thresholds of the origin of ventricular extrasystole, paroxysmal ventricular tachysystole and ventricular fibrillation in long-term stimulation of the ventromedial hypothalamic nucleus were studied in experiments on rabbits. It was found that myocardial resistance to the development of arrhythmias depended on the manifestation of the sympathetico-parasympathic interaction on the heart. In predominance of parasympathetic effects on the heart during hypothalamic stimulation, the threshold of the origin of arrhythmia increased by 40% for ventricular extrasystole, by 38% for paroxysmal ventricular tachysystole and by more than 36% for ventricular fibrillation. In predominance of sympathetic effects during stimulation of negative emotiogenic hypothalamic centers, the threshold of arrhythmia origin decreased by 45% for ventricular extrasystole, by 32% for paroxysmal ventricular tachysystole and by 24% for ventricular fibrillation.
在对家兔的实验中，研究了长期刺激腹内侧下丘脑核时室性期前收缩、阵发性室性心动过速和心室颤动起始阈值的变化动态。发现心肌对心律失常发展的抵抗力取决于心脏交感 - 副交感相互作用的表现。在下丘脑刺激期间，当副交感神经对心脏的作用占优势时，室性期前收缩的心律失常起始阈值增加40%，阵发性室性心动过速增加38%，心室颤动增加超过36%。在刺激负性情绪发生性下丘脑中心期间，当交感神经作用占优势时，室性期前收缩的心律失常起始阈值降低45%，阵发性室性心动过速降低32%，心室颤动降低24%。
