Binz H
Klin Wochenschr. 1979 Jun 15;57(12):625-30. doi: 10.1007/BF01477629.
The present article summarizes briefly our knowledge of antigen-specific B- and T-lymphocyte receptors. Antigen-specific receptors on mammalian B-lymphocytes are mainly monomeric IgM and IgD consisting of conventional immunoglobulin heavy and light chains. The nature of the T-lymphocyte receptors which can specifically recognize antigens is not yet fully defined but it seems that conventional light chains do not participate in the build up of this receptor. However, T-lymphocytes express two polypeptide chains which bear variable domains sharing idiotypic determinants with the corresponding B-lymphocytes. These Tau chains can bind the corresponding antigen.
本文简要总结了我们对抗抗原特异性B淋巴细胞和T淋巴细胞受体的认识。哺乳动物B淋巴细胞上的抗原特异性受体主要是由传统免疫球蛋白重链和轻链组成的单体IgM和IgD。能够特异性识别抗原的T淋巴细胞受体的性质尚未完全明确，但传统轻链似乎不参与该受体的组成。然而，T淋巴细胞表达两条多肽链，其可变区与相应的B淋巴细胞具有共同的独特型决定簇。这些Tau链可以结合相应的抗原。
