Nutt D, Montgomery S A
School of Medical Sciences, University of Bristol, UK.
Int Clin Psychopharmacol. 1996 Jun;11 Suppl 3:77-82. doi: 10.1097/00004850-199606003-00013.
Social phobia is a common disorder which is associated with considerable suffering and impairment. Effective treatments have now been developed and they represent an important advance in the management of the disorder. Moclobemide is a reversible inhibitor of monoamine oxidase A (RIMA) which has an established place in the treatment of depression. The efficacy of moclobemide in social phobia has been demonstrated in short-term treatment for up to 12 weeks in three placebo-controlled studies. It has also proved to be effective in long-term treatment in a placebo-controlled study and in open treatment studies. This paper reviews the efficacy of moclobemide in social phobia.
社交恐惧症是一种常见的疾病，会带来相当大的痛苦和功能损害。目前已开发出有效的治疗方法，这代表了该疾病治疗方面的一项重要进展。吗氯贝胺是一种单胺氧化酶A可逆抑制剂（RIMA），在抑郁症治疗中已有既定地位。在三项安慰剂对照研究中，吗氯贝胺治疗社交恐惧症的疗效已在长达12周的短期治疗中得到证实。在一项安慰剂对照研究和开放治疗研究中，它在长期治疗中也被证明是有效的。本文综述了吗氯贝胺治疗社交恐惧症的疗效。
