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膝关节类风湿关节炎的关节镜灌洗治疗

Arthroscopic lavage treatment in rheumatoid arthritis of the knee.

作者信息

Sharma A, Baethge B A, Acebes J C, Lisse J R

机构信息

Department of Internal Medicine, University of Texas Medical Branch at Galveston 77555-0759, USA.

出版信息

J Rheumatol. 1996 Nov;23(11):1872-4.

PMID:8923370
Abstract

OBJECTIVE

To assess the efficacy of outpatient arthroscopic lavage in rheumatoid arthritis (RA) of the knee.

METHODS

9 patients with RA and active synovitis of at least one knee were selected. All patients were taking disease modifying antirheumatic drugs and nonsteroidal antiinflammatory drugs and had failed intraarticular corticosteroid injection of the knee. Using the 1.9 mm office arthroscope and strict sterile technique the affected knee was lavaged with at least 750 cc of normal saline. At the end of the procedure 40 mg triamcinolone acetonide was injected through the arthroscope. Assessment was done at baseline and 4, 8, and 12 weeks after the lavage using a visual analog scale for pain and 50 foot walk time.

RESULTS

8 of the 9 patients showed marked improvement in their pain and walk time. This effect was maintained at least 12 weeks after the procedure.

CONCLUSION

Office arthroscopic lavage treatment is beneficial in a selected group of patients. This procedure is simple and well tolerated without major complications, and may be an option when more conservative therapies have failed.

摘要

目的

评估门诊关节镜灌洗治疗膝关节类风湿关节炎(RA)的疗效。

方法

选取9例患有RA且至少一个膝关节存在活动性滑膜炎的患者。所有患者均在服用改善病情抗风湿药和非甾体抗炎药,且膝关节腔内注射皮质类固醇治疗无效。使用1.9毫米的门诊关节镜并采用严格的无菌技术,用至少750毫升生理盐水对患侧膝关节进行灌洗。在操作结束时,通过关节镜注射40毫克曲安奈德。在灌洗前及灌洗后4周、8周和12周,使用视觉模拟疼痛量表和50英尺步行时间进行评估。

结果

9例患者中有8例在疼痛和步行时间方面有显著改善。这种效果在术后至少维持了12周。

结论

门诊关节镜灌洗治疗对部分选定患者有益。该操作简单,耐受性良好,无重大并发症,当更保守的治疗方法失败时,可能是一种选择。

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