O'Brien M G, Withrow S J, Straw R C, Powers B E, Kirpensteijn J K
Departments of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, USA.
Vet Surg. 1996 Nov-Dec;25(6):471-9. doi: 10.1111/j.1532-950x.1996.tb01445.x.
Total or partial orbitectomy were used to treat 24 dogs and six cats with invasive periorbital tumors. The surgical procedure and clinical results were evaluated in this retrospective study. The most common types of tumors treated in this series of patients were multilobular osteochondrosarcoma and squamous cell carcinoma. Two patients died of cardiopulmonary arrest within 24 hours after surgery. One patient developed neurological signs after total orbitectomy that resolved with conservative therapy. Minor complications, which included infection, strabismus, and conjunctivitis, occurred in seven patients. Regrowth of tumor in the periorbital region occurred in 11 patients (36.7%). Tumor resection by orbitectomy provided local disease-free interval of more than 1 year in more than 50% of patients. Survival rate for the first year was 70.4% in this series of patients as determined by life table analysis. Orbitectomy requires detailed knowledge of regional anatomy and experience with performing a combination of surgical procedures. Preoperative diagnostic tests should include imaging techniques to define the extent of the disease. When performed properly, orbitectomy is a valuable procedure that can be used to effectively treat invasive tumors of the orbit.
采用全眶切除术或部分眶切除术治疗24只犬和6只猫的眼眶周围浸润性肿瘤。在这项回顾性研究中对手术过程和临床结果进行了评估。该系列患者中治疗的最常见肿瘤类型为多叶性骨软骨肉瘤和鳞状细胞癌。2例患者在术后24小时内死于心肺骤停。1例患者在全眶切除术后出现神经症状,经保守治疗后缓解。7例患者出现了包括感染、斜视和结膜炎在内的轻微并发症。11例患者(36.7%)眼眶周围区域肿瘤复发。通过眶切除术进行肿瘤切除使超过50%的患者局部无病生存期超过1年。根据生命表分析,该系列患者第一年的生存率为70.4%。眶切除术需要对局部解剖有详细了解,并具备实施联合手术的经验。术前诊断检查应包括影像学技术以明确疾病范围。如果操作得当,眶切除术是一种可用于有效治疗眼眶浸润性肿瘤的有价值的手术。