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[腮腺同步双肿瘤]

[Synchronous double tumors of the parotid gland].

作者信息

Franzen A, Koegel K

机构信息

Klinik für HNO-Krankheiten und Plastische Wiederherstellungschirurgie, Katholisches Krankenhaus Essen-Werden.

出版信息

Laryngorhinootologie. 1996 Jul;75(7):437-40. doi: 10.1055/s-2007-997610.

DOI:10.1055/s-2007-997610
PMID:8924174
Abstract

BACKGROUND

Synchronous unilateral tumors of the parotid gland are found only rarely. The majority of these are multifocal Warthin's tumors (papillary cystadema lymphomatosum). The incidence is reported to range up to 12%. Malignant processes develop within a pleomorphic adenoma in about 6.6% of all cases. In a few cases, they also develop in a Warthin's tumor. Two coexisting benign parotid tumors of different histologic types are extremely rare.

PATIENTS

In this report we present a patient with an unilateral pleomorphic adenoma and a Warthin's tumor. It is the eleventh published case of this kind. The problems of diagnosis, differential diagnosis, and surgical therapy of benign multiple parotid tumors are discussed. The current literature is reviewed.

RESULTS

Synchronous multiple Warthin's Tumors or multiple tumors of different histologic types in the same parotid gland are found rarely. Nevertheless careful preoperative diagnosis causing B-mode ultrasound as the primary imaging modality. Meticulous intraoperative inspection and palpation of the glandular tissue and periglandular lymph nodes is indicated. In order to ensure adequate tumor removal, the therapy of choice is a total or subtotal parotidectomy.

CONCLUSION

We suggest careful preoperative diagnosis and meticolous intra-operative exploration in order to localize multifocal lesions of benign parotid tumors. This minimizes the chance of overlooking synchronous tumor foci, which would necessitate difficult revision surgery entailing a risk of injury to the facial nerve.

摘要

背景

腮腺同步性单侧肿瘤极为罕见。其中大多数为多灶性沃辛瘤(乳头状淋巴囊腺瘤)。据报道,其发病率高达12%。在所有病例中,约6.6%的多形性腺瘤会发生恶性病变。在少数情况下,恶性病变也会在沃辛瘤中发生。两种不同组织学类型的腮腺良性肿瘤并存极为罕见。

患者

在本报告中,我们介绍了一名患有单侧多形性腺瘤和沃辛瘤的患者。这是此类已发表的第11例病例。讨论了腮腺多发良性肿瘤的诊断、鉴别诊断及手术治疗问题。并对当前文献进行了综述。

结果

在同一腮腺中发现同步性多发沃辛瘤或不同组织学类型的多发肿瘤极为罕见。尽管如此,术前应仔细诊断,以B超作为主要影像学检查手段。术中需仔细检查和触诊腺组织及腺周淋巴结。为确保肿瘤完全切除,首选治疗方法是全腮腺或次全腮腺切除术。

结论

我们建议术前仔细诊断并在术中进行细致探查,以定位腮腺良性肿瘤的多灶性病变。这样可将遗漏同步肿瘤灶的可能性降至最低,否则可能需要进行困难的翻修手术,且有损伤面神经的风险。

相似文献

1
[Synchronous double tumors of the parotid gland].[腮腺同步双肿瘤]
Laryngorhinootologie. 1996 Jul;75(7):437-40. doi: 10.1055/s-2007-997610.
2
Synchronous unilateral parotid neoplasms. A case report.同步性单侧腮腺肿瘤。病例报告。
Med Oral Patol Oral Cir Bucal. 2009 Feb 1;14(2):E90-2.
3
Synchronous unilateral parotid gland neoplasms of three different histological types.三种不同组织学类型的同步性单侧腮腺肿瘤。
Auris Nasus Larynx. 2007 Jun;34(2):263-6. doi: 10.1016/j.anl.2006.07.001. Epub 2006 Aug 30.
4
Uncommon Coexistence of Pleomorphic Adenoma and Warthin's Tumor in a Painfully Swollen Left Parotid Gland: A Surgical Case Report.左腮腺肿痛性肿块中罕见共存多形性腺瘤和沃辛瘤:一例外科手术病例报告。
Am J Case Rep. 2023 Nov 30;24:e940985. doi: 10.12659/AJCR.940985.
5
Poorly differentiated carcinoma arising in a Warthin's tumor of the parotid gland: pathogenesis, histopathology, and surgical management of malignant Warthin's tumors.腮腺沃辛瘤中发生的低分化癌:恶性沃辛瘤的发病机制、组织病理学及外科治疗
Am Surg. 2007 Apr;73(4):397-9.
6
[Multiple primary pleomorphic adenomas of the unilateral parotid gland].[单侧腮腺多原发性多形性腺瘤]
Laryngorhinootologie. 2007 Jun;86(6):448-50. doi: 10.1055/s-2006-945134. Epub 2007 Jan 11.
7
Multiple primary tumours of the parotid gland.腮腺多原发性肿瘤。
Int J Oral Maxillofac Surg. 2004 Sep;33(6):531-4. doi: 10.1016/j.ijom.2004.03.010.
8
Warthin's tumor-associated neoplasms: report of two cases and review of the literature.沃辛瘤相关肿瘤:两例报告并文献复习
Ear Nose Throat J. 1993 Apr;72(4):264-9, 272-3.
9
Synchronous oncocytoma and Warthin's tumor in the ipsilateral parotid gland.同侧腮腺内的同步嗜酸细胞瘤和沃辛瘤。
Auris Nasus Larynx. 2004 Mar;31(1):73-8. doi: 10.1016/j.anl.2003.07.008.
10
[Bilateral adenolymphoma (Warthin's tumor) of the parotid. The anatomicoclinical, diagnostic and therapeutic aspects of 2 cases].[腮腺双侧腺淋巴瘤(沃辛瘤)。2例的解剖临床、诊断及治疗方面]
Minerva Stomatol. 1994 Nov;43(11):535-42.

引用本文的文献

1
Uncommon Coexistence of Pleomorphic Adenoma and Warthin's Tumor in a Painfully Swollen Left Parotid Gland: A Surgical Case Report.左腮腺肿痛性肿块中罕见共存多形性腺瘤和沃辛瘤:一例外科手术病例报告。
Am J Case Rep. 2023 Nov 30;24:e940985. doi: 10.12659/AJCR.940985.
2
Two case reports of synchronous unilateral pleomorphic adenoma and cystadenolymphoma of the parotid gland with literature review.腮腺同步性单侧多形性腺瘤和腺淋巴瘤两例报告并文献复习
J Ultrason. 2018;18(75):369-373. doi: 10.15557/JoU.2018.0055.
3
Sialometaplasia arising in the ectopic salivary gland ductal inclusions of multiple intraparotid lymph nodes.
多灶性腮腺内淋巴结异位涎腺导管包涵体中发生的涎腺化生。
J Clin Pathol. 2004 Dec;57(12):1335-7. doi: 10.1136/jcp.2004.017202.
4
[Diagnosis and prognosis of salivary gland tumors. An interpretation of new revised WHO classification].[唾液腺肿瘤的诊断与预后。对世界卫生组织新修订分类的解读]
Mund Kiefer Gesichtschir. 1997 Sep;1(5):252-67. doi: 10.1007/BF03043562.