Toppino M, Corno F, Serra G C, Mistrangelo M, Guglielminotti P, Bolla C, Comba A, Capuzzi P, Morino F
Istituto di Clinica Chirurgica, Università degli Studi Torino.
Minerva Gastroenterol Dietol. 1996 Sep;42(3):161-7.
Gastrinoma is a rare neoplasia producing gastrina, the hormone responsible of the clinic manifestations related to Zollinger-Ellison syndrome. The localization of gastrinoma is pancreatic or extrapancreatic (usually in Stabile and Passaro triangle). We present a case report concerning an extra-pancreatic gastrinoma not localized in this area and included in a lymph node. This is an extremely infrequent localization (2.4%). There are two different opinions about this localization. Some authors think that this is always a secondary lesion of a small primary neoplasia usually asymptomatic. Other authors think that there are primary lymph nodal gastrinomas that could be safely removed with excision of lymph node. The infrequent localisation of this case induced us to report this experience in order to contribute to the comprehension of this pathology.
胃泌素瘤是一种罕见的产生胃泌素的肿瘤,胃泌素是导致卓-艾综合征相关临床表现的激素。胃泌素瘤的定位在胰腺内或胰腺外(通常位于斯塔比尔和帕萨罗三角区)。我们报告一例胰腺外胃泌素瘤的病例,该肿瘤并非位于此区域而是位于一个淋巴结内。这种定位极其罕见(2.4%)。关于这种定位存在两种不同观点。一些作者认为这始终是一个通常无症状的小原发性肿瘤的继发性病变。其他作者则认为存在原发性淋巴结胃泌素瘤,通过切除淋巴结可安全切除。该病例罕见的定位促使我们报告这一经验,以有助于对这种病理情况的理解。