Pedron P, Desgrandchamps F, Hoffmann P, Lesourd A, Billebaud T, Teillac P, Le Duc A
Service d'Urologie, Hôpital Saint-Louis, Paris, France.
Prog Urol. 1996 Aug-Sep;6(4):569-72.
Keratinized squamous cell metaplasia of the renal pelvis (KSMRP) is a rare lesion, difficult to differentiate from urothelial tumour on the basis of the usual morphological examinations. It is therefore usually diagnosed retrospectively, on histological examination of a nephroureterectomy specimen. However, as its benign nature justifies conservative treatment, preoperative recognition of this lesion is essential. Upper urinary tract endoscopy, which allows diagnosis and treatment of this disease, is therefore very important in this context. Endoscopy is indicated when KSMRP is suspected clinically in a doubtful case of urothelial tumour of the upper urinary tract, in a context of passage of soft stones or a history of renal stones or upper urinary tract infection. Ureteroscopy constitutes the first step to confirm the diagnosis. It must be completed by a percutaneous procedure to eradicate any residual lesion, which could be responsible for recurrence. We report a case of KSMRP in a solitary kidney treated by retrograde and percutaneous endoscopic surgery.
肾盂角化性鳞状上皮化生（KSMRP）是一种罕见病变，基于常规形态学检查难以与尿路上皮肿瘤相鉴别。因此，通常是在对肾输尿管切除标本进行组织学检查时作出回顾性诊断。然而，鉴于其良性性质支持保守治疗，术前识别该病变至关重要。上尿路内镜检查可对该病进行诊断和治疗，因此在这种情况下非常重要。当临床上怀疑为上尿路尿路上皮肿瘤的可疑病例中存在KSMRP，且伴有软结石排出或有肾结石或上尿路感染病史时，应进行内镜检查。输尿管镜检查是确诊的第一步。必须通过经皮手术来根除任何可能导致复发的残留病变。我们报告1例采用逆行和经皮内镜手术治疗的孤立肾KSMRP病例。
