Nolard N
Section de Mycologie, Institut d'Hygiène et d'Epidémiologie, Bruxelles, Belgique.
Bull Acad Natl Med. 1996 Apr;180(4):849-56; discussion 856-8.
The growing incidence of nosocomial invasive aspergillosis is related with the development of new therapies and the presence of Aspergillus spores in the patients'vicinity. Earth moving, demolition or renovation works adjacent to or inside the hospital are undoubtfully implied in this process. Potted plants and individual sachets of ground pepper distributed to patients are another significant source of Aspergillus spores. The extrinsic and multiple causes of hospital contamination may explain the numerous problems in our studies of strain typing, whatever the methods used (phenotype and genotype).
医院获得性侵袭性曲霉病发病率的不断上升与新疗法的发展以及患者周围存在曲霉菌孢子有关。医院附近或内部进行的土方工程、拆除或翻新工程无疑与此过程有关。分发给患者的盆栽植物和单独的胡椒粉包是曲霉菌孢子的另一个重要来源。医院污染的外在和多种原因可能解释了我们在菌株分型研究中遇到的众多问题，无论使用何种方法（表型和基因型）。
