兔眼房水中神经肽Y的水平。

Neuropeptide Y levels in the aqueous humor of rabbits.

作者信息

Hirota A, Gregory D S

机构信息

Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut, USA.

出版信息

J Ocul Pharmacol Ther. 1996 Spring;12(1):51-6. doi: 10.1089/jop.1996.12.51.

DOI:10.1089/jop.1996.12.51

PMID:8925397

Abstract

The concentration of neuropeptide Y in the aqueous humor (NPYaq) did not change during the circadian cycle in rabbits. However, NPYaq also did not decrease after superior cervical ganglionectomy or preganglionic section of the cervical sympathetic trunk (decentralization). Nor did NPYaq change after either stimulation, with para-aminoclonidine, or blockade, with rauwolscine, of prejunctional ocular alpha2-adrenergic receptors. Therefore, NPYaq does not reflect NPY release from ocular sympathetic nerves in rabbits.

摘要

兔眼房水中神经肽Y（NPYaq）的浓度在昼夜节律周期中没有变化。然而，在颈上神经节切除术或颈交感干节前切断术（去神经支配）后，NPYaq也没有降低。在用对氨基可乐定刺激或用萝芙辛阻断节前眼α2-肾上腺素能受体后，NPYaq也没有改变。因此，NPYaq不能反映兔眼交感神经释放的NPY。