Colarinha P, Fonseca A T, Salgado L, Vieira M R
Department of Nuclear Medicine, Portuguese Institute of Oncology, Lisbon, Portugal.
Clin Nucl Med. 1996 Apr;21(4):299-301. doi: 10.1097/00003072-199604000-00008.
Scintigraphy using Tc-99m MDP and Tl-201 was performed in a patient with polyostotic Paget's disease and sarcomatous degeneration in the right iliac bone. Tc-99m MDP imaging showed abnormal uptake in both types of lesions. Tl-201 imaging showed increased uptake in the sarcomatous lesion and absent uptake in pagetic lesions. This result supports the idea that Tl-201 scintigraphy may have a potential role to play in the differentiation of Paget's disease from malignancy. To the authors' knowledge, Tl-201 has never been reported for the detection of sarcomatous change of pagetic bone.
对一名患有多骨型佩吉特病且右髂骨发生肉瘤样变的患者进行了使用锝-99m亚甲基二膦酸盐（Tc-99m MDP）和铊-201（Tl-201）的骨闪烁显像。Tc-99m MDP显像显示两种类型的病变均有异常摄取。Tl-201显像显示肉瘤样病变摄取增加，而佩吉特病变无摄取。这一结果支持了Tl-201骨闪烁显像可能在佩吉特病与恶性肿瘤的鉴别中发挥潜在作用的观点。据作者所知，尚未有关于使用Tl-201检测佩吉特骨的肉瘤样变的报道。
