冷暴露对大鼠棕色脂肪组织中多巴胺含量的影响。
Influence of cold exposure on dopamine content in rat brown adipose tissue.
作者信息
Blouquit M F, Gripois D, Roffi J
机构信息
Laboratoire d'Endocrinologie, Université Paris-Sud, Orsay, France.
出版信息
Horm Metab Res. 1996 Mar;28(3):122-7. doi: 10.1055/s-2007-979143.
Cold exposure produces a large increase in rat brown adipose tissue (BAT) dopamine (DA) content. This increase is rapid (30 min of cold are sufficient to produce a maximal effect), and can be detected at different ages (from birth to adulthood). Cold also greatly increases DA turnover rate in BAT. In the same experimental conditions tyrosine hydroxylase is activated, while the activity of dopamine-beta-hydroxylase is not modified. The possibility that DA can regulate BAT functioning is discussed.
冷暴露会使大鼠棕色脂肪组织（BAT）中的多巴胺（DA）含量大幅增加。这种增加速度很快（30分钟的冷暴露足以产生最大效应），并且在不同年龄段（从出生到成年）都能检测到。冷暴露还会极大地提高棕色脂肪组织中多巴胺的周转率。在相同的实验条件下，酪氨酸羟化酶被激活，而多巴胺-β-羟化酶的活性未发生改变。文中讨论了多巴胺调节棕色脂肪组织功能的可能性。
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