胃癌内镜下胃活检组织的碳水化合物含量
Carbohydrate content of endoscopic gastric biopsies in carcinoma of the stomach.
作者信息
Machado G, Clamp J R, Read A E
出版信息
Gut. 1977 Aug;18(8):670-2. doi: 10.1136/gut.18.8.670.
Abstract
An investigation of the glycoproteins of gastric mucus from biopsies of patients with gastric cancer has shown a change in certain carbohydrate components. There is a significant increase (P less than 0-001) in mannose and a significant decrease in N-acetylgalactosamine in both secretors and non-secretors from cancer-free and cancer-bearing regions of the stomach as compared with normal stomachs. The possible reasons for this change and its relation to two possible glycoprotein fractions are discussed.
摘要
对胃癌患者活检所得胃黏液糖蛋白的一项研究显示，某些碳水化合物成分发生了变化。与正常胃相比，无论分泌型还是非分泌型，来自胃的无癌区域和患癌区域的样本中，甘露糖显著增加（P小于0.001），而N-乙酰半乳糖胺显著减少。文中讨论了这种变化的可能原因及其与两种可能的糖蛋白组分的关系。
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