O'Shea M F, Saling M M, Bladin P F, Berkovic S F
Department of Psychology, University of Melbourne, Australia.
J Clin Exp Neuropsychol. 1996 Feb;18(1):98-109. doi: 10.1080/01688639608408266.
The present study evaluated the hypothesis (Mayeux et al., 1980) that visual confrontation naming deficits may underlie the memory complaint in patients with temporal lobe epilepsy (TLE). Thirty-nine patients with medically refractory left (n = 23) and right (n = 16) TLE were compared with an epilepsy control group with idiopathic primary generalized epilepsy (n = 38). All subjects completed selected subtests of the Multilingual Aphasia Examination and Wechsler Memory Scale (Form 1) together with a measure specifically designed for quantification of the memory complaint in TLE. Objective verbal memory test performance, confrontation naming, repetition, and comprehension were unrelated to memory self-report. Controlled Oral Word Association was the only measure to exert an influence on memory self-ratings, and this relationship was specific to the TLE group. The hypothesis of Mayeux et al. (1980) was not specifically supported, but the present findings do suggest that cognitive processes reflected in orthographically based and internally generated word retrieval play a role in memory self-report.
本研究对如下假设(Mayeux等人,1980年)进行了评估:视觉对答命名缺陷可能是颞叶癫痫(TLE)患者记忆主诉的潜在原因。将39例药物难治性左侧(n = 23)和右侧(n = 16)颞叶癫痫患者与一组患有特发性原发性全身性癫痫的癫痫对照组(n = 38)进行了比较。所有受试者都完成了《多语言失语症检查》和韦氏记忆量表(第一版)的选定子测试,以及一项专门设计用于量化颞叶癫痫患者记忆主诉的测量。客观言语记忆测试表现、对答命名、复述和理解与记忆自我报告无关。受控口语单词联想是唯一对记忆自我评分有影响的测量方法,且这种关系仅在颞叶癫痫组中存在。Mayeux等人(1980年)的假设未得到明确支持,但目前的研究结果确实表明,基于正字法和内部生成的单词检索所反映的认知过程在记忆自我报告中发挥作用。