亚油酸甲酯氢过氧化物对小鼠自然杀伤细胞介导的细胞毒性的影响。
Effect of methyl linoleate hydroperoxides on murine natural killer cell-mediated cytotoxicity.
作者信息
Oarada M, Kurita N, Terao K, Miyaji M
机构信息
Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan.
出版信息
J Nutr Sci Vitaminol (Tokyo). 1995 Dec;41(6):707-11. doi: 10.3177/jnsv.41.707.
PMID:8926542
Abstract
Methyl linoleate hydroperoxides (MLHPO), a model for lipid hydroperoxides, suppressed murine natural killer (NK) cell-mediated cytotoxicity to YAC-1 cells. When NK cells were cultured with MLHPO, the conjugation of NK cells could not lyse YAC-1 cells. These findings suggest that NK cell-mediated cytotoxicity can be suppressed by lipid hydroperoxides.
摘要
亚油酸甲酯氢过氧化物（MLHPO）作为脂质氢过氧化物的模型，可抑制小鼠自然杀伤（NK）细胞对YAC-1细胞的细胞毒性作用。当NK细胞与MLHPO共同培养时，NK细胞的结合不能裂解YAC-1细胞。这些发现表明脂质氢过氧化物可抑制NK细胞介导的细胞毒性作用。
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