Tran H H
Service des Urgences, Hôpital Nhi Dong 2 Grall, Hô Chi Minh Ville, Vietnam.
Med Trop (Mars). 1996;56(2):167-9.
Poisonings due to organophosphate insecticides are a common accident with serious consequences in Vietnam. In this report we describe a case due to ingestion of carbamate by a 4 years old boy. Muscarinic and nicotinic manifestations appeared within 90 minutes after ingestion. In addition to evacuation of the stomach and oxygenotherapy, treatment consisted of high dose atropine: 1,396 capsules in 18 days (349 mg). The authors review the mechanisms of poisoning which leads to accumulation of acetylcholine in nerve endings and emphasize the need for preventive measures in developing countries where use of this type of insecticide is widespread.
在越南,有机磷杀虫剂中毒是一种常见且后果严重的意外事件。在本报告中,我们描述了一名4岁男孩因摄入氨基甲酸盐而中毒的病例。摄入后90分钟内出现了毒蕈碱样和烟碱样症状。除了洗胃和氧疗外,治疗还包括大剂量阿托品:18天内服用1396粒胶囊(349毫克)。作者回顾了导致乙酰胆碱在神经末梢积聚的中毒机制,并强调在广泛使用这类杀虫剂的发展中国家采取预防措施的必要性。