Popović L, Momcilović A, Jajić D, Cigić T, Vuleković P
Neurohirurska klinika, Institut za hirurgiju, Medicinski fakultet, Novi Sad.
Med Pregl. 1996;49(7-8):296-9.
81 patients with expansive lesion in the optic chiasm region were reviewed. Pituitary adenomas were diagnosed in 37 patients: 5 with acromegaly, 2 with prolactinoma and the remaining 30 with hormone inactive adenomas. Meningiomas were diagnosed in 39, craniopharyngiomas in 4 patients and chordoma in one patient. The most common symptom was visual disturbance in 86%, but headache, hormonal disturbance occurred as well. All patients with adenomas were endocrinologically evaluated after detailed ophthalmologic and neurologic examinations. 28 patients were transcranially operated, 5 transsfenoidally and transcranially and 4 only transfenoidally. After endocrinologic reevaluation all patients with adenomas had undergone postoperative radiotherapy. Tumor recurrence was diagnosed in 14 patients, while 6 patients underwent reoperation. The approach to surgical regimen depended on the size and localization of meningioma. Unilateral subfrontal approach was most frequent (35). Subtotal tumor ablation was performed in 5 (13%) patients. Craniopharyngiomas were diagnosed in 4 patients (2 adults and 2 children). Total tumor ablation was performed only in one case.
回顾性分析了81例视交叉区域存在占位性病变的患者。37例诊断为垂体腺瘤:5例肢端肥大症,2例催乳素瘤,其余30例为无功能垂体腺瘤。39例诊断为脑膜瘤,4例颅咽管瘤,1例脊索瘤。最常见的症状为视力障碍(86%),但也有头痛、激素紊乱等症状。所有垂体腺瘤患者在进行详细的眼科和神经科检查后均接受了内分泌评估。28例患者接受了开颅手术,5例经蝶窦和开颅手术,4例仅行经蝶窦手术。在内分泌重新评估后,所有垂体腺瘤患者均接受了术后放疗。14例患者诊断为肿瘤复发,6例患者接受了再次手术。手术方案的选择取决于脑膜瘤的大小和位置。最常用的是单侧额下入路(35例)。5例(13%)患者进行了肿瘤次全切除。4例患者(2例成人和2例儿童)诊断为颅咽管瘤。仅1例进行了肿瘤全切除。