[Immunologic response in patients with atopic dermatitis].

It is a well known fact that atopic dermatitis, as one of the clinical manifestations of atopic syndrome, is characterized by a number of immunologic disorders. In 17 patients with atopic dermatitis we examined: systemic cellular immunity, production of total serum IgE, specific IgE to certain aero-allergens, cutaneous hypersensitivity of an early type to aero-allergens and chemotaxis activity of neutrophils and monocytes. Increased production of IgE proved to be the main disorder which confirms increased values of the total IgE in serum, specific IgE to inhalatory allergens and cutaneous hypersensitivity of an early type to inhalatory allergens in 11 (64.70%) patients. In regard to aero-allergens the most common atopics are pollens and Dermatophagoides pteronyssinus. Decreased number of CD8+ T-lymphocytes and decreased chemotaxis activity of neutrophils was established in some cases.