Napoli V, Tozzini A, Neri E, Calderazzi A, Gabriele M, Bonaretti S, Vinci G, Vitali C, Molea N
Cattedra di Radiologia, Università degli Studi, Pisa.
Minerva Stomatol. 1996 Apr;45(4):141-8.
The aim of the present study was to evaluate the sensitivity and specificity of the ultrasonography, in comparison with other methods of investigation (scintigraphy, sialography, and biopsy), in scanning morphostructural changes in the parotid gland in patient with Sjögren's syndrome. During the period June-October 1994, 34 patients (5 males and 29 females, age ranged between 20 and 88 years) with "sicca syndrome" underwent to echography, scintigraphy, sialography and biopsy. The diagnosis was confirmed or excluded using the European Community Epidemiologic Committee criteria for Sjögren's syndrome. Twenty-two patients out of 34 were affected by Sjögren's syndrome, while the others resulted as control subjects. The ultrasonographic investigation has shown 76.19% of sensitivity and 30.43% of specificity. Even if echography is a non-invasive method, which could be used as preliminary approach for studying the diffused involvement of the parotid gland, at the status of the art, it is not completely reliable for the global evaluation of the morphostructural changes in patients with Sjögren's syndrome, in comparison with the other techniques. Because of the double nature of the gland injury, it appears to be essential the diagnostic integration between echography and sialography.
本研究的目的是评估超声检查与其他检查方法(闪烁扫描、涎管造影和活检)相比,对干燥综合征患者腮腺形态结构变化的扫描敏感性和特异性。在1994年6月至10月期间,34例“干燥综合征”患者(5例男性,29例女性,年龄在20至88岁之间)接受了超声检查、闪烁扫描、涎管造影和活检。根据欧洲共同体流行病学委员会的干燥综合征标准确诊或排除诊断。34例患者中有22例患有干燥综合征,其余作为对照。超声检查显示敏感性为76.19%,特异性为30.43%。尽管超声检查是一种非侵入性方法,可作为研究腮腺弥漫性受累的初步方法,但就目前的技术水平而言,与其他技术相比,它对于干燥综合征患者形态结构变化的全面评估并不完全可靠。由于腺体损伤的双重性质,超声检查和涎管造影之间的诊断整合似乎至关重要。