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[1例采用血管内手术治疗的多发性脑真菌性动脉瘤]

[A case of multiple cerebral mycotic aneurysms treated with endovascular surgery].

作者信息

Katakura K, Kayama T, Kondo R, Kureyama H, Maruya J, Nakajima M, Nakai O, Hosoya T, Yamaguchi K

机构信息

Department of Surgical Neurology, Yamagata University School of Medicine.

出版信息

No Shinkei Geka. 1995 Dec;23(12):1127-32.

PMID:8927222
Abstract

A case of multiple mycotic cerebral aneurysms successfully treated with endovascular surgery is reported. A nine-year-old boy who has suffered from hypertrophic obstructive cardiomyopathy and active infectious endocarditis in the mitral valve developed sudden consciousness disturbance and convulsion. Computerized tomography revealed subarachnoid hemorrhage with subcortical hematoma in the left parietal lobe. Angiography demonstrated four aneurysms at the distal part of the middle cerebral artery on both sides. Since his physical status had been deteriorating, it was difficult to undergo a usual surgical operation. Therefore, endovascular surgery was performed. The catheter was super-selectively advanced to the parent artery of the left posterior parietal artery aneurysm which seemed to be the hemorrhagic source, and the embolization was performed using platinum coils and liquid embolization material. Angiography after embolization showed that the aneurysms had been successfully occupied by the materials while the aneurysm of the right anterior parietal artery had not responded antibiotic therapy. Therefore the second embolization was carried out to the parent artery of the aneurysm of the right anterior parietal artery one month later. The patient had no neurological deficit after embolization and no aneurysms have been detected by the follow-up angiogram after the second embolization. An endovascular approach might be an alternative useful treatment for cases in which the patient has, deteriorated so much that it is considered difficult to perform open craniotomy under general anesthesia.

摘要

报道了一例采用血管内手术成功治疗的多发性霉菌性脑动脉瘤病例。一名9岁男孩患有肥厚性梗阻性心肌病和二尖瓣活动性感染性心内膜炎,突然出现意识障碍和惊厥。计算机断层扫描显示蛛网膜下腔出血伴左侧顶叶皮质下血肿。血管造影显示双侧大脑中动脉远端有4个动脉瘤。由于他的身体状况一直在恶化,难以进行常规手术。因此,进行了血管内手术。将导管超选择性推进到似乎是出血源的左后顶叶动脉动脉瘤的供血动脉,并使用铂金线圈和液体栓塞材料进行栓塞。栓塞后的血管造影显示动脉瘤已被材料成功填充,而右前顶叶动脉的动脉瘤对抗生素治疗无反应。因此,一个月后对右前顶叶动脉动脉瘤的供血动脉进行了第二次栓塞。栓塞后患者无神经功能缺损,第二次栓塞后的随访血管造影未发现动脉瘤。对于患者身体状况恶化到难以在全身麻醉下进行开颅手术的病例,血管内治疗可能是一种有用的替代治疗方法。

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