Majima K
Department of Ophthalmology, Fujita Health University School of Medicine, Aichi, Japan.
Ophthalmic Res. 1995;27(6):356-65. doi: 10.1159/000267748.
While epidermal growth factor (EGF) has been found to exist in the human aqueous humor, which is necessary for maintaining the physiological condition of the lens, our immunohistochemical study confirmed the presence of EGF receptors and EGF in human lens epithelial cells (LECs), with EGF promoting growth potential and morphological change of the cells. Based on these findings, we feel that the effect of EGF upon human LECs is related to the movement of the cells in vivo.
虽然已发现表皮生长因子（EGF）存在于人类房水中，而房水对于维持晶状体的生理状态是必需的，但我们的免疫组织化学研究证实了人类晶状体上皮细胞（LECs）中存在EGF受体和EGF，且EGF可促进这些细胞的生长潜能和形态变化。基于这些发现，我们认为EGF对人类LECs的作用与体内细胞的移动有关。
