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[一名死于类Goodpasture综合征的青少年的急性坏死性毛细血管炎]

[Acute necrotizing capillaritis in an adolescent dying from a a Goodpasture-like pulmonary-renal syndrome].

作者信息

Maresi E, Becchina G, Orlando E, Ottoveggio G

机构信息

Istituto di Anatomia Patologica, Universit di Palermo.

出版信息

Pathologica. 1995 Dec;87(6):666-71.

PMID:8927428
Abstract

In this report the authors describe a rare case of pulmonary/renal syndrome like-Goodpasture's disease characterized by a necrotizing acute capillaritis in the lung, kidney, liver, spleen and heart. In the heart the capillaritis was associated with a contiguous acute ischemic lesion. The clinical and pathologic findings of the case suggest that the presence of vasculitis should not exclude a diagnosis of Goodpasture's Syndrome and that the multisystemic capillaritis would demonstrate the organ-non-specificity of anti-glomerular/alveolar basement membrane antibody.

摘要

在本报告中,作者描述了一例罕见的类似肺出血肾炎综合征(Goodpasture病)的肺/肾综合征病例,其特征为肺、肾、肝、脾和心脏出现坏死性急性毛细血管炎。在心脏中,毛细血管炎与相邻的急性缺血性病变相关。该病例的临床和病理表现提示,血管炎的存在不应排除肺出血肾炎综合征的诊断,且多系统毛细血管炎将显示抗肾小球/肺泡基底膜抗体的器官非特异性。

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