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甲型、乙型和丙型急性病毒性肝炎患者血清中β2-微球蛋白水平

[Level of beta 2-microglobulin in serum of patients with acute viral hepatitis types A, B and C].

作者信息

Tomasiewicz K, Jagiełło-Wójtowicz E, Krawczuk G, Lyczak A, Baran E, Rzeszowska G

机构信息

Katedra i Klinika Chorób Zakaźnych AM w Lublinie.

出版信息

Przegl Epidemiol. 1996;50(3):259-64.

PMID:8927736
Abstract

Serum beta 2-microglobulin concentrations were assayed in 14 patients with acute hepatitis A, 16 with acute hepatitis B and 10 with hepatitis C. Serum samples were taken from each patient in the first and the second week of hospitalization and in the period of aminotransferase normalization. There was a significant increase of beta 2-microglobulin level in every type of hepatitis compared to the control group. A raised serum beta 2-microglobulin concentration persisted during convalescent period. It decreased gradually in type A and B of hepatitis. Serum beta 2-microglobulin level during convalescence in hepatitis C was similar to that of first weeks of hospitalization.

摘要

对14例甲型急性肝炎患者、16例乙型急性肝炎患者和10例丙型肝炎患者的血清β2-微球蛋白浓度进行了检测。在患者住院的第一周和第二周以及转氨酶恢复正常期间采集血清样本。与对照组相比,每种类型的肝炎患者β2-微球蛋白水平均显著升高。在恢复期,血清β2-微球蛋白浓度持续升高。在甲型和乙型肝炎中,该浓度逐渐下降。丙型肝炎恢复期的血清β2-微球蛋白水平与住院第一周时相似。

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