Bailey M J, Johnston C L, Yates C J, Somerville P G, Dormandy J A
Lancet. 1979 Jul 28;2(8135):168-70. doi: 10.1016/s0140-6736(79)91434-x.
Simple factors which may serve as predictors of the success or failure of amputations in the feet were examined in 59 consecutive diabetics. Age, sex, method of diabetic control, smoling, presence of neuropathy or peripheral pulses, preoperative blood-urea, and temperature did not correlate with success of amuptations. The average preoperative white-cell count and blood-sugar were higher in the failure group (p less than 0.01 and p less than 0.05 respectively), but there was considerable overlap between the groups. By contrast, the preoperative haemoglobin level was significantly lower (p less than 0.001) in patients whose amputations healed than in those with failure of healing, both at the digital and metatarsal or transmetatarsal levels; also, there was very little overlap in haemoglobin levels between the success and failure groups. All 18 amputations done in patients with a preoperative haemoglobin less than 12.0 g/dl were successful, whilst all 30 amputations in those with a preoperative level greater than 13.0 g/dl failed.
对59例连续性糖尿病患者足部截肢手术成败的一些简单预测因素进行了研究。年龄、性别、糖尿病控制方法、吸烟、神经病变或外周脉搏情况、术前血尿素和体温与截肢手术的成功与否均无关联。失败组术前白细胞计数和血糖平均值较高(分别为p<0.01和p<0.05),但两组之间有相当程度的重叠。相比之下,无论是在趾部还是跖骨或经跖骨水平,截肢愈合患者的术前血红蛋白水平显著低于愈合失败患者(p<0.001);而且,成功组与失败组的血红蛋白水平几乎没有重叠。术前血红蛋白低于12.0 g/dl的患者所做的18例截肢手术全部成功,而术前水平高于13.0 g/dl的患者所做的30例截肢手术全部失败。