Metak G, Scherer M A
Abteilung für Allgemein- und Unfallchirurgie des Städtischen Krankenhauses München-Bogenhausen.
Unfallchirurg. 1996 Jul;99(7):477-86.
At present no established therapy for the complete loss of meniscus is available. An attempt is made to create a transplant out of autogeneic tissue resembling the meniscus in its morphological and functional aspects. The middle third of the patellar tendon with proximal and distal bone blocks serves as a basis and is coated with a fascia lata strip. After temporary subcutaneous transfer, the meniscus substitute is intended for later transplantation. The theoretical ideas for the imitation of a meniscus in view of fibre architecture and biomechanical validity were tested in 14 sheep. In principal this model succeeds in imitating the fibre architecture of the menisci. After a conditioning period of 8-10 weeks in the subcutaneous tissue, the neomeniscus seems to be suitable for transplantation. The tensile strength of the grafts decreases slightly but the bone blocks stay viable.
目前，对于半月板完全缺失尚无成熟的治疗方法。人们尝试用在形态和功能方面类似于半月板的自体组织制作移植体。带近端和远端骨块的髌腱中三分之一作为基础，并覆盖一条阔筋膜条带。经过临时皮下转移后，半月板替代物准备用于后期移植。针对纤维结构和生物力学有效性方面模仿半月板的理论构想在14只绵羊身上进行了测试。原则上，该模型成功模仿了半月板的纤维结构。在皮下组织经过8至10周的适应期后，新半月板似乎适合移植。移植物的拉伸强度略有下降，但骨块仍保持存活。
