Rabinovich E I, Sokolova S N
Vopr Onkol. 1996;42(4):45-8.
The report deals with the predictive value of a procedure for lifetime detection of tumor in experimental animals. The database included the results of regular cAMP/cHMP tests carried out in 54 rats with radionuclide-inducted tumors and 24 tumor-free rats. The data were processes by statistical methods and the informative value was determined on the basis of standard recommendations. The test was shown to have high sensitivity (85.2%), sufficient predictive value (73%) and diagnostic effectiveness (68%). Application of the test in groups of humans at high risk of tumor development is discussed.
该报告探讨了一种用于实验动物肿瘤终身检测程序的预测价值。数据库包含了对54只患有放射性核素诱导肿瘤的大鼠和24只无肿瘤大鼠进行的常规cAMP/cHMP测试结果。数据采用统计方法进行处理，并根据标准建议确定其信息价值。结果表明，该测试具有高灵敏度（85.2%）、足够的预测价值（73%）和诊断有效性（68%）。文中还讨论了该测试在肿瘤发生高危人群中的应用。
