Altman C
AANA J. 1996 Feb;64(1):41-7.
Carbon monoxide is a colorless, odorless, and tasteless gas that, when inhaled, is toxic to humans. In 1965, Middleton reported the detection of carbon monoxide in the closed anesthetic circuits of patients undergoing surgery. In recent years, anesthesia providers from at least four American hospitals have reported instances of intraoperative carbon monoxide poisoning in anesthetized patients undergoing surgery. Although no deaths were associated with these incidents, carboxyhemoglobin levels ranged from 8.5% to 32%. In virtually all reported cases, the incidents occurred in surgical suites that had not been used for at least 2 days. This facet of the phenomenon advanced the theory that a slow chemical reaction, probably involving soda lime or barium hydroxide lime, was responsible for the liberation of carbon monoxide within the anesthesia circuit. Recent research has attributed this generation of carbon monoxide to the degradation of volatile anesthetic agents by desiccated carbon dioxide absorbents. Although carbon monoxide poisoning of patients undergoing anesthesia with volatile anesthetics is probably a rare occurrence, it is a potential problem for all anesthesia providers.
一氧化碳是一种无色、无味、无臭的气体，吸入后对人体有毒。1965年，米德尔顿报告在接受手术患者的封闭式麻醉回路中检测到一氧化碳。近年来，至少四家美国医院的麻醉医护人员报告了接受手术的麻醉患者术中发生一氧化碳中毒的病例。尽管这些事件未导致死亡，但碳氧血红蛋白水平在8.5%至32%之间。在几乎所有报告的病例中，事件都发生在至少两天未使用过的手术套房中。这一现象的这一方面推动了一种理论，即一种可能涉及苏打石灰或氢氧化钡石灰的缓慢化学反应是麻醉回路中一氧化碳释放的原因。最近的研究将这种一氧化碳的产生归因于干燥的二氧化碳吸收剂对挥发性麻醉剂的降解。尽管使用挥发性麻醉剂进行麻醉的患者发生一氧化碳中毒可能很少见，但这对所有麻醉医护人员来说都是一个潜在问题。
