Simoncelli C, Molini E, Ricci G, Capolunghi B, Alunni N
Istituto di Clinical Otorinolaringoiatrica e Chirurgia Cervicofacciale, Università di Perugia.
Acta Otorhinolaryngol Ital. 1995 Apr;15(2):80-6.
Distortion Product Otoacoustic Emissions (DPOEs) are otoacoustic emissions evoked by two pure equilevel tones (f1, f2) called primaries and are believed to provide frequency-specific information regarding cochlear function. We recorded DPOEs at 2f1-f2 frequency with a constant frequency ration (f2/f1 = 1.22) in 8 normal hearing subjects (16 ears, mean age 28 +/- 1.5) to establish the characteristics of these emissions in the adult population. DPOEs were measured at the following F2 frequencies and respective fp geometric mean frequencies: 696/632, 1001/904, 1501/1360, 2002/1809, 3003/2714, 4004/3626, 5005/4531 e 6006/5435 Hz. Detailed testing included the recording of DPOE "audiograms" and input-output functions depicting the relationship of the amplitudes of DPOE to primary-tone levels ranging from 25 to 70 dB SPL in 5 dB steps. The present findings are in good agreement with investigations based on evoked otoacoustic emissions published by other researchers. The average DPOE "audiograms" demonstrated a low-frequency maximum at 1501 Hz (f2)/1360 (fp) and a high-frequency peak at 5005 Hz (f2)/4531 (fp). The two maximum regions were separated by a minimum around 3003 Hz (f2)/2714 (fp). This study confirms the feasibility of DPOE measurements among adults and provide a normal baseline for this age group. DPOEs could be useful, in association with evoked otoacoustic emissions and with auditory brainstem responses, in obtaining a precise evaluation of the peripheral auditory system.
畸变产物耳声发射（DPOEs）是由两个称为原信号的纯等强度音调（f1、f2）诱发的耳声发射，被认为能提供有关耳蜗功能的频率特异性信息。我们在8名听力正常的受试者（16只耳，平均年龄28±1.5岁）中，以恒定频率比（f2/f1 = 1.22）在2f1 - f2频率下记录DPOEs，以确定成年人群中这些发射的特征。在以下F2频率和相应的fp几何平均频率下测量DPOEs：696/632、1001/904、1501/1360、2002/1809、3003/2714、4004/3626、5005/4531和6006/5435 Hz。详细测试包括记录DPOE“听力图”以及输入 - 输出函数，这些函数描绘了DPOE幅度与原信号音调水平（范围为25至70 dB SPL，步长为5 dB）之间的关系。目前的研究结果与其他研究人员发表的基于诱发耳声发射的研究结果高度一致。平均DPOE“听力图”在1501 Hz（f2）/1360（fp）处显示出低频最大值，在5005 Hz（f2）/4531（fp）处显示出高频峰值。这两个最大值区域被一个在3003 Hz（f2）/2714（fp）左右的最小值隔开。本研究证实了在成年人中进行DPOE测量的可行性，并为该年龄组提供了正常基线。DPOEs与诱发耳声发射和听觉脑干反应相结合，可能有助于获得对外周听觉系统的精确评估。
