Begara Morillas F, Silmi Moyano A, Hermida Gutiérrez J, Chicharro Almarza J, Fernández Aceñero M J, Martín Rodilla C, Ramírez Fernández J C, Rapariz González M, Salinas Casado J, Resel Estévez L
Cátedra y Servicio de Urología, Hospital Universitario San Carlos, Madrid, España.
Arch Esp Urol. 1996 Jul-Aug;49(6):562-70.
Six cases of genitourinary lymphoma are described and the literature reviewed.
METHODS/RESULTS: The cases had the following histopathological diagnosis: 1 small and large cell non-Hodgkin lymphoma (NHL) of the renal pelvis, 2 high grade centroblastic testicular NHL; 1 centroblastic-centroid bladder NHL, 1 lymphoplasmocytoid bladder NHL and 1 low grade NHL of the prostate. All but the prostatic lymphoma were primary. Treatment was by nephrectomy and chop polychemotherapy (PCT) for the renal pelvis NHL, orchiectomy for the 2 testicular NHLs (one case also received radiotherapy), chop PCT for the bladder NHLs and PCT for the prostatic NHL. Three patients have died: the patient with renal pelvis NHL, centroblastic-centroid bladder NHL and the patient with prostatic NHL.
Although these tumors are rare, they should be suspected in patients with lymphoma, elderly men with a testicular mass, patients with a large bladder compressing/infiltrating mass and in the immunnodepressed patients. A preoperative histopathological diagnosis must be made before performing radical surgery.
描述6例泌尿生殖系统淋巴瘤病例并复习相关文献。
方法/结果：这些病例的组织病理学诊断如下：1例肾盂小细胞和大细胞非霍奇金淋巴瘤（NHL），2例高级别中心母细胞性睾丸NHL；1例中心母细胞-中心粒细胞性膀胱NHL，1例淋巴浆细胞样膀胱NHL和1例前列腺低级别NHL。除前列腺淋巴瘤外，其余均为原发性。治疗方法为：肾盂NHL行肾切除术及CHOP多药联合化疗（PCT），2例睾丸NHL行睾丸切除术（1例还接受了放疗），膀胱NHL行CHOP PCT，前列腺NHL行PCT。3例患者死亡：肾盂NHL患者、中心母细胞-中心粒细胞性膀胱NHL患者和前列腺NHL患者。
尽管这些肿瘤罕见，但对于淋巴瘤患者、有睾丸肿块的老年男性、有巨大膀胱压迫/浸润性肿块的患者以及免疫功能低下的患者应怀疑有此类肿瘤。在进行根治性手术前必须做出术前组织病理学诊断。
