Shaffer-Bailey M, Greenleaf J E, Hutchinson T M
Ames Research Center, NASA, Moffett Field, CA 94035-1000, USA.
Aviat Space Environ Med. 1996 Jan;67(1):46-51.
To determine weight (water) loss levels for onset of muscular strength and endurance changes during deconditioning.
Seven men (27-40 yr) performed maximal shoulder-, knee-, and ankle-joint isometric (0 degree.s(-1) load) and isokinetic (60 degrees, 120 degrees, 180 degrees.s(-1) velocity) exercise tests during ambulatory control (AC), after 6 h of 6 degrees head-down tilt (HDT; dry-bulb temp. = 23.2 +/- SD 0.6 degrees C, relative humidity = 31.1+/- 11.1%) and after 6 h of 80 degrees foot-down head-out water immersion (WI; water temp. = 35.0 +/- SD 0.1 degree C) treatments.
Weight (water) loss after HDT (1.10 +/- SE 0.14 kg, 1.4 +/- 0.2% body wt) and WI (1.54+/- 0.19 kg, 2.0 +/- 0.2% body wt) were not different, but urinary excretion with WI (1,354 +/- 142 ml.6 h(-1)) was 28% greater (p < 0.05) than that of 975 +/- 139 ml.6 h(-1) with HDT. Muscular endurance (total work; maximal flexion-extension of the non-dominant knee at 180 degrees.s(-1) for 30 s) was not different between AC and the WI or HDT treatments. Shoulder-, knee-, and ankle-joint strength was unchanged except for three knee-joint peak torques: AC torque (120 degrees.s(-1), 285 +/- 20 Nm) decreased to 268 +/- 21 Nm (delta = -6%, p < 0.05) with WI; and AC torques (180 degrees.s(-1), 260 +/- 19 Nm) decreased to 236 +/- 15 Nm (delta = -9%, p < 0.01) with HDT, and to 235 +/- 19 Nm (delta = -10%, p < 0.01) with WI.
Thus, the total body hypohydration threshold level for shoulder- and ankle-joint strength and endurance decrements is more than 2% body weight (water) loss, while significant reduction in knee-joint muscular strength-endurance occurred only at moderate (120 degrees.s(-1) and lighter (180 degrees.s(-1)) loads with body weight loss of 1.4-2.0% following WI or HDT, respectively. These weight (water) losses and knee-joint strength decrements are somewhat less than the mean weight loss of 2.6% and knee-joint strength decrements of 6-20% of American astronauts after Skylab flights to 84 d.
确定在去适应过程中,肌肉力量和耐力开始发生变化时的体重(水分)流失水平。
七名男性(27 - 40岁)在动态对照(AC)期间、6小时6°头低位倾斜(HDT;干球温度 = 23.2 ± 标准差0.6°C,相对湿度 = 31.1 ± 11.1%)后以及80°脚向下头露出水面的水浸(WI;水温 = 35.0 ± 标准差0.1°C)处理6小时后,进行了最大肩部、膝部和踝关节等长(0度·秒⁻¹负荷)和等速(60度、120度、180度·秒⁻¹速度)运动测试。
HDT后(1.10 ± 标准误0.14千克,1.4 ± 0.2%体重)和WI后(1.54 ± 0.19千克,2.0 ± 0.2%体重)的体重(水分)流失无差异,但WI后的尿量排泄(1354 ± 142毫升·6小时⁻¹)比HDT后的(975 ± 139毫升·6小时⁻¹)高28%(p < 0.05)。AC与WI或HDT处理之间的肌肉耐力(总功;非优势膝在180度·秒⁻¹下最大屈伸30秒)无差异。肩部、膝部和踝关节力量无变化,但有三个膝关节峰值扭矩除外:AC扭矩(120度·秒⁻¹,285 ± 20牛米)在WI后降至268 ± 21牛米(变化量 = -6%,p < 0.05);AC扭矩(180度·秒⁻¹,260 ± 19牛米)在HDT后降至236 ± 15牛米(变化量 = -9%,p < 0.01),在WI后降至235 ± 19牛米(变化量 = -10%,p < 0.01)。
因此,肩部和踝关节力量及耐力下降的全身脱水阈值水平超过2%体重(水分)流失,而膝关节肌肉力量耐力的显著降低仅在中等(120度·秒⁻¹)和较轻(180度·秒⁻¹)负荷下分别在WI或HDT后体重减轻1.4 - 2.0%时出现。这些体重(水分)流失和膝关节力量下降略低于美国宇航员在天空实验室飞行84天后平均2.6%的体重减轻和6 - 20%的膝关节力量下降。