Tiberge M
Laboratoire du Sommeil, CHU Rangueil, Toulouse.
Encephale. 1995 Dec;21 Spec No 7:29-33.
Although the clinical symptoms of severe depression are easily recognized, this is not always the case in minimal forms or in certain masked depressions. Failure to respond to appropriate treatment may then be taken to indicate the possible existence of specific and organic sleep disorders with clinical symptoms similar to those of depressive illness. Sleep disorders mainly comprise sleep apnea and periodic movement of the lower limbs. Diagnosis can only be confirmed by EPS before a specific treatment is selected : correct diagnosis of the disorder is essential, particularly for sleep apnea, since standard drug therapy for depression and anxiety disorders often includes benzodiazepines, which, through the depressant effect they exert on the respiratory centers, only worsen symptoms.
尽管重度抑郁症的临床症状很容易识别,但在轻度形式或某些隐匿性抑郁症中情况并非总是如此。对适当治疗无反应可能会被视为存在特定的器质性睡眠障碍,其临床症状与抑郁症相似。睡眠障碍主要包括睡眠呼吸暂停和下肢周期性运动。只有通过多导睡眠图(EPS)才能确诊,然后再选择特定的治疗方法:正确诊断该疾病至关重要,尤其是对于睡眠呼吸暂停,因为治疗抑郁症和焦虑症的标准药物疗法通常包括苯二氮䓬类药物,这些药物会对呼吸中枢产生抑制作用,只会使症状恶化。