Tamburro A M, Scatturin A, Del Pra A
Int J Pept Protein Res. 1977;9(5):310-8.
The conformational properties of (Pro-Phe-Gly)n and (Phe-Pro-Gly)n were investigated both in the solid state and in solution. In solid state X-ray diffraction patterns seem to indicate that (Pro-Phe-Gly)n assumes a single chain triple helical structure. In solution, by circular dichroism studies, it was possible to show the existence of beta-bends in the presence of ethylene glycol. Similar studies carried out on (Phe-Pro-Gly)n showed no collagen or polyproline II-like structure in the solid state. In solution the beta-bend formation was apparent in all the solvent systems studied.
研究了（脯氨酸-苯丙氨酸-甘氨酸）n和（苯丙氨酸-脯氨酸-甘氨酸）n在固态和溶液中的构象性质。在固态下，X射线衍射图谱似乎表明（脯氨酸-苯丙氨酸-甘氨酸）n呈现单链三螺旋结构。在溶液中，通过圆二色性研究发现，在乙二醇存在的情况下存在β-转角。对（苯丙氨酸-脯氨酸-甘氨酸）n进行的类似研究表明，其在固态下不存在胶原蛋白或聚脯氨酸II样结构。在溶液中，在所研究的所有溶剂体系中β-转角的形成都很明显。
