Shiba K, Umezaki T, Zheng Y, Miller A D
Rockefeller University, New York, NY 10021-6399, USA.
Neuroreport. 1996 Sep 2;7(13):2139-42. doi: 10.1097/00001756-199609020-00015.
A new animal model is described for the study of fictive vocalization, evoked by electrical stimulation of the periaqueductal grey (PAG) in decerebrate, paralyzed and artificially ventilated cats. Changes in activities of the phrenic, abdominal, recurrent and superior laryngeal nerves induced by PAG stimulation after induction of paralysis were compared with the activities of these nerves or the muscles innervated by them during actual vocalization induced before paralysis. The PAG-induced respiratory and laryngeal motor pattern in paralyzed cats is similar to that of PAG-induced vocalization. Furthermore, the switch from inspiration to vocal-like activity is usually synchronized with lung inflation in both paradigms. It is concluded that fictive vocalization can be induced by PAG stimulation in paralyzed cats.
本文描述了一种新的动物模型，用于研究在去大脑、麻痹并人工通气的猫中，由电刺激中脑导水管周围灰质（PAG）诱发的虚构发声。将麻痹诱导后PAG刺激引起的膈神经、腹神经、喉返神经和喉上神经活动的变化，与麻痹前实际发声期间这些神经或其支配肌肉的活动进行比较。麻痹猫中PAG诱导的呼吸和喉部运动模式与PAG诱导的发声相似。此外，在两种模式下，从吸气到类似发声活动的转换通常与肺充气同步。得出的结论是，PAG刺激可在麻痹猫中诱发虚构发声。
