抗生素林可霉素的半合成修饰 - Suppr

Suppr

超能文献

Semisynthetic modification of antibiotic lincomycin.

作者信息

Sztaricskai F, Dinya Z, Puskás M M, Batta G, Masuma R, Omura S

机构信息

Research Group for Antibiotics of the Hungarian Academy of Sciences, L. Kossuth University, Debrecen, Hungary.

出版信息

J Antibiot (Tokyo). 1996 Sep;49(9):941-3. doi: 10.7164/antibiotics.49.941.

DOI:10.7164/antibiotics.49.941

PMID:8931731

Abstract

摘要

相似文献

Semisynthetic modification of antibiotic lincomycin.

J Antibiot (Tokyo). 1996 Sep;49(9):941-3. doi: 10.7164/antibiotics.49.941.

Chemical synthesis and structural study of lincomycin sulfoxides and a sulfone.

J Antibiot (Tokyo). 1997 Oct;50(10):866-73. doi: 10.7164/antibiotics.50.866.

Synthesis of novel lincomycin derivatives and their in vitro antibacterial activities.

J Antibiot (Tokyo). 2013 Mar;66(3):195-8. doi: 10.1038/ja.2012.107. Epub 2012 Dec 12.

Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 2. Synthesis of 7(S)-7-deoxy-7-(4-morpholinocarbonylphenylthio)lincomycin and its 3-dimensional analysis with rRNA.

J Antibiot (Tokyo). 2016 Jun;69(6):428-39. doi: 10.1038/ja.2015.125. Epub 2015 Dec 16.

Synthesis and antibacterial activity of novel lincomycin derivatives. II. Exploring (7S)-7-(5-aryl-1,3,4-thiadiazol-2-yl-thio)-7-deoxylincomycin derivatives.

J Antibiot (Tokyo). 2017 May;70(5):655-663. doi: 10.1038/ja.2016.139. Epub 2016 Dec 7.

Synthesis and antibacterial activity of novel lincomycin derivatives. I. Enhancement of antibacterial activities by introduction of substituted azetidines.

J Antibiot (Tokyo). 2016 Jun;69(6):440-5. doi: 10.1038/ja.2015.134. Epub 2016 Jan 13.

Synthesis and SARs of novel lincomycin derivatives Part 5: optimization of lincomycin analogs exhibiting potent antibacterial activities by chemical modification at the 6- and 7-positions.

J Antibiot (Tokyo). 2018 Feb;71(2):298-317. doi: 10.1038/ja.2017.114. Epub 2017 Nov 1.

Lincomycin, clindamycin and their applications.

Appl Microbiol Biotechnol. 2004 May;64(4):455-64. doi: 10.1007/s00253-003-1545-7. Epub 2004 Feb 5.

Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 1. Newly generated antibacterial activities against Gram-positive bacteria with erm gene by C-7 modification.

J Antibiot (Tokyo). 2016 May;69(5):368-80. doi: 10.1038/ja.2015.119. Epub 2015 Dec 16.

Structural modification of the lincomycin antibiotic.

J Antibiot (Tokyo). 1999 Nov;52(11):1050-5. doi: 10.7164/antibiotics.52.1050.

引用本文的文献

Squaramide Tethered Clindamycin, Chloroquine, and Mortiamide Hybrids: Design, Synthesis, and Antimalarial Activity.

ACS Med Chem Lett. 2023 Jan 25;14(2):217-222. doi: 10.1021/acsmedchemlett.2c00531. eCollection 2023 Feb 9.

Synthesis and antibacterial activity of novel lincomycin derivatives. IV. Optimization of an N-6 substituent.

J Antibiot (Tokyo). 2017 Dec;70(12):1112-1121. doi: 10.1038/ja.2017.143. Epub 2017 Nov 8.

Synthesis and SARs of novel lincomycin derivatives Part 5: optimization of lincomycin analogs exhibiting potent antibacterial activities by chemical modification at the 6- and 7-positions.

J Antibiot (Tokyo). 2018 Feb;71(2):298-317. doi: 10.1038/ja.2017.114. Epub 2017 Nov 1.

Synthesis and antibacterial activity of novel lincomycin derivatives. III. Optimization of a phenyl thiadiazole moiety.

J Antibiot (Tokyo). 2017 Jul 5. doi: 10.1038/ja.2017.59.

Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 4: synthesis of novel lincomycin analogs modified at the 6- and 7-positions and their potent antibacterial activities.

J Antibiot (Tokyo). 2017 Jul;70(8):888-906. doi: 10.1038/ja.2017.54. Epub 2017 May 31.

Synthesis and structure-activity relationships of novel lincomycin derivatives part 3: discovery of the 4-(pyrimidin-5-yl)phenyl group in synthesis of 7(S)-thiolincomycin analogs.

J Antibiot (Tokyo). 2017 Jan;70(1):52-64. doi: 10.1038/ja.2016.114. Epub 2016 Oct 5.

Synthesis and antibacterial activity of novel lincomycin derivatives. I. Enhancement of antibacterial activities by introduction of substituted azetidines.

J Antibiot (Tokyo). 2016 Jun;69(6):440-5. doi: 10.1038/ja.2015.134. Epub 2016 Jan 13.

Synthesis and structure-activity relationships of novel lincomycin derivatives. Part 1. Newly generated antibacterial activities against Gram-positive bacteria with erm gene by C-7 modification.

J Antibiot (Tokyo). 2016 May;69(5):368-80. doi: 10.1038/ja.2015.119. Epub 2015 Dec 16.

J Antibiot (Tokyo). 2016 Jun;69(6):428-39. doi: 10.1038/ja.2015.125. Epub 2015 Dec 16.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验