阴沟肠杆菌PB2中季戊四醇四硝酸酯还原酶的序列与特性
Sequence and properties of pentaerythritol tetranitrate reductase from Enterobacter cloacae PB2.
作者信息
French C E, Nicklin S, Bruce N C
机构信息
Institute of Biotechnology, University of Cambridge, United Kingdom.
出版信息
J Bacteriol. 1996 Nov;178(22):6623-7. doi: 10.1128/jb.178.22.6623-6627.1996.
Abstract
Pentaerythritol tetranitrate reductase, which reductively liberates nitrite from nitrate esters, is related to old yellow enzyme. Pentaerythritol tetranitrate reductase follows a ping-pong mechanism with competitive substrate inhibition by NADPH, is strongly inhibited by steroids, and is capable of reducing the unsaturated bond of 2-cyclohexen-1-one.
摘要
季戊四醇四硝酸酯还原酶可从硝酸酯中还原释放出亚硝酸盐，它与老黄色酶相关。季戊四醇四硝酸酯还原酶遵循乒乓机制，受NADPH竞争性底物抑制，受类固醇强烈抑制，并且能够还原2-环己烯-1-酮的不饱和键。
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2
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3
Sequences in the -35 region of Escherichia coli rpoS-dependent genes promote transcription by E sigma S.大肠杆菌中依赖rpoS的基因-35区域的序列促进E sigma S介导的转录。
J Bacteriol. 1996 May;178(10):2785-93. doi: 10.1128/jb.178.10.2785-2793.1996.
4
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Biochem J. 1995 Dec 15;312 ( Pt 3)(Pt 3):671-8. doi: 10.1042/bj3120671.
5
Old Yellow Enzyme. The discovery of multiple isozymes and a family of related proteins.老黄色酶。多种同工酶和相关蛋白家族的发现。
J Biol Chem. 1993 Mar 25;268(9):6097-106.
6
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Proc Natl Acad Sci U S A. 1994 Feb 1;91(3):922-6. doi: 10.1073/pnas.91.3.922.
7
alpha/beta barrel evolution and the modular assembly of enzymes: emerging trends in the flavin oxidase/dehydrogenase family.α/β桶状结构的进化与酶的模块化组装：黄素氧化酶/脱氢酶家族的新趋势
Bioessays. 1994 Feb;16(2):115-22. doi: 10.1002/bies.950160208.
8
Purification and characterization of morphinone reductase from Pseudomonas putida M10.恶臭假单胞菌M10中吗啡酮还原酶的纯化与特性分析
Biochem J. 1994 Jul 1;301 ( Pt 1)(Pt 1):97-103. doi: 10.1042/bj3010097.
9
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Structure. 1994 Nov 15;2(11):1089-105.
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J Biol Chem. 1995 Feb 3;270(5):1983-91. doi: 10.1074/jbc.270.5.1983.
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