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骨髓移植后一名儿童脑部发生播散性镰刀菌属感染。

Disseminated Fusarium sp. infection affecting the brain of a child after bone marrow transplantation.

作者信息

Bleggi-Torres L F, de Medeiros B C, Neto J Z, Loddo G, Telles F Q, de Medeiros C R, Pasquini R

机构信息

Department of Medical Pathology, Hospital de Clínicas, UFPR, Curitiba, Brazil.

出版信息

Bone Marrow Transplant. 1996 Nov;18(5):1013-5.

PMID:8932859
Abstract

A case of Fusarium sp. infection of the brain in a 6-year-old child who underwent allogeneic BMT is reported. As far as the authors know, this is the first report of Fusarium sp. encephalitis in a BMT patient. Fusarium sp. infection is a rare but emerging fungal pathogen after BMT and, because of several similarities, it is often mistaken for other mold infections, such as Aspergillus sp. The importance of early identification of this fungus as a cause of disseminated fungal infection in BMT patients, and some new modalities of Fusarium sp disseminated infection treatment are discussed here.

摘要

报告了1例6岁接受异基因骨髓移植的儿童发生镰刀菌属脑感染的病例。据作者所知,这是骨髓移植患者中首例镰刀菌属脑炎报告。镰刀菌属感染是骨髓移植后一种罕见但正在出现的真菌病原体,由于存在一些相似之处,它常被误诊为其他霉菌感染,如曲霉菌属感染。本文讨论了早期识别这种真菌作为骨髓移植患者播散性真菌感染病因的重要性,以及镰刀菌属播散性感染治疗的一些新方法。

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Bone Marrow Transplant. 1996 Nov;18(5):1013-5.
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Mycopathologia. 2023 Dec;188(6):973-981. doi: 10.1007/s11046-023-00790-6. Epub 2023 Aug 31.
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Fungal infections of the CNS: treatment strategies for the immunocompromised patient.中枢神经系统真菌感染:免疫功能低下患者的治疗策略
CNS Drugs. 2007;21(4):293-318. doi: 10.2165/00023210-200721040-00004.