Drury V, Birchwood M, Cochrane R, Macmillan F
Archer Centre, All Saints Hospital, Birmingham.
Br J Psychiatry. 1996 Nov;169(5):602-7. doi: 10.1192/bjp.169.5.602.
A trial of CT in acute psychosis conducted by the authors has shown a significant impact on the rate and degree of recovery of positive symptoms, the focus of the intervention. This paper seeks to determine whether these effects generalise to other features of acute psychosis including dysphoria, insight and "low level' psychotic thinking which were not directly targeted.
Measures of dysphoria, insight and psychotic thinking were taken over a six-month period following presentation for acute psychosis. Using survival analysis, time to recovery from psychosis using three definitions of increasing stringency was compared between the CT and control group.
CT was associated with a 25-50% reduction in recovery time depending on the definition used.
The impact of the CT intervention extended beyond positive symptoms to include insight, dysphoria and "low level' psychotic thinking. Nevertheless this kind of "clinical' recovery required a median of 20 weeks to complete. Implications for clinical models of acute care are discussed.
作者进行的一项关于急性精神病患者CT治疗的试验表明，该治疗对阳性症状（干预重点）的恢复速度和程度有显著影响。本文旨在确定这些效果是否适用于急性精神病的其他特征，包括烦躁不安、洞察力和“低水平”的精神病性思维，这些特征并非直接干预的目标。
在急性精神病患者就诊后的六个月内，对烦躁不安、洞察力和精神病性思维进行测量。使用生存分析，比较了CT组和对照组在使用三种不同严格程度定义的情况下从精神病中恢复的时间。
根据所使用的定义，CT治疗使恢复时间缩短了25%-50%。
CT干预的影响不仅限于阳性症状，还包括洞察力、烦躁不安和“低水平”的精神病性思维。然而，这种“临床”恢复平均需要20周才能完成。文中讨论了对急性护理临床模型的影响。
