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布比卡因脊髓麻醉后听力丧失

Hearing loss following spinal anaesthesia with bupivacaine.

作者信息

Hussain S S, Heard C M, Bembridge J L

机构信息

Department of Otolaryngology, Freeman Hospital, Newcastle upon Tyne, UK.

出版信息

Clin Otolaryngol Allied Sci. 1996 Oct;21(5):449-54. doi: 10.1046/j.1365-2273.1996.00827.x.

DOI:10.1046/j.1365-2273.1996.00827.x
PMID:8932952
Abstract

The purpose of this study was to determine the incidence, degree and reversibility of hearing loss following spinal anaesthesia with bupivacaine and secondarily to see if there is a relationship between post-spinal headache and hearing loss. A prospective series of 35 patients admitted for elective Caesarean section under a standardized spinal anaesthetic was investigated. Otolaryngological examination and pure tone audiometry in the frequency range 250 Hz to 8 KHz were done on the day before surgery and on post-operative days 1 and 5. Five patients developed a reversible sensorineural hearing loss (mean loss 14.6 dB). This loss was either unilateral (3) or bilateral (2) and affected the low frequencies in all five patients. The demographic data for both groups (i.e. no change in hearing/sensorineural loss) was similar for age, weight, height, blood pressure change and level of sensory block. There was no association found with post-spinal headache.

摘要

本研究的目的是确定布比卡因蛛网膜下腔麻醉后听力损失的发生率、程度及可逆性,其次是观察蛛网膜下腔头痛与听力损失之间是否存在关联。对35例行标准化蛛网膜下腔麻醉择期剖宫产的患者进行了前瞻性研究。在手术前一天以及术后第1天和第5天进行了耳鼻喉科检查和250Hz至8kHz频率范围内的纯音听力测定。5例患者出现可逆性感音神经性听力损失(平均损失14.6dB)。这种损失为单侧(3例)或双侧(2例),且所有5例患者的低频均受影响。两组(即听力无变化/感音神经性损失)的人口统计学数据在年龄、体重、身高、血压变化和感觉阻滞水平方面相似。未发现与蛛网膜下腔头痛有关联。

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Hearing loss following spinal anaesthesia with bupivacaine.布比卡因脊髓麻醉后听力丧失
Clin Otolaryngol Allied Sci. 1996 Oct;21(5):449-54. doi: 10.1046/j.1365-2273.1996.00827.x.
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Anaesthesia. 2011 May;66(5):341-7. doi: 10.1111/j.1365-2044.2011.06662.x. Epub 2011 Mar 18.

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Ann Indian Acad Neurol. 2022 Nov-Dec;25(6):1218-1220. doi: 10.4103/aian.aian_433_22. Epub 2022 Dec 3.
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Cross-sectional study on hearing loss and auditory reaction time before and after spinal anesthesia with marcaine 0.5% in patients undergoing elective surgery.对接受择期手术患者使用0.5%布比卡因进行脊髓麻醉前后听力损失和听觉反应时间的横断面研究。
Ann Med Surg (Lond). 2020 Nov 1;60:236-240. doi: 10.1016/j.amsu.2020.10.046. eCollection 2020 Dec.
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[Acute neural hearing loss after cervical spine injection treatment].
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HNO. 2018 Nov;66(11):843-846. doi: 10.1007/s00106-018-0537-y.