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麻醉中的知晓:发生率、后果及预防

Awareness in anaesthesia: incidence, consequences and prevention.

作者信息

Heier T, Steen P A

机构信息

Department of Anesthesiology, Ullevaal University Hospital, Oslo, Norway.

出版信息

Acta Anaesthesiol Scand. 1996 Oct;40(9):1073-86. doi: 10.1111/j.1399-6576.1996.tb05569.x.

Abstract

Awareness during anaesthesia is a state of consciousness that is revealed by explicit or implicit memory of intraoperative events. Although large clinical surveys indicate an incidence of explicit awareness of < 0.3% during anaesthesia for general surgery, this adverse effect should be a great concern, because patients may be permanently disabled by the experience of being awake during surgery. Prevention of awareness during anaesthesia starts with an appropriate preoperative visit to the patient. The anaesthetic delivery machines must be properly checked before and during anaesthesia. The anaesthetic depth should be assessed by observation of movement responses, and consequently a minimum of muscle relaxants used. Because the anaesthetic depth can be controlled by determination of endtidal drug concentration, volatile inhaled anaesthesia may be associated with a lower frequency of awareness than other anaesthetic regimens.

摘要

麻醉期间知晓是一种意识状态,可通过对术中事件的显性或隐性记忆表现出来。尽管大型临床调查表明,普通外科手术麻醉期间显性知晓的发生率低于0.3%,但这种不良影响仍应引起高度关注,因为患者可能因手术中清醒的经历而永久性致残。预防麻醉期间知晓始于术前对患者进行适当的访视。麻醉给药设备在麻醉前和麻醉期间必须进行妥善检查。应通过观察运动反应来评估麻醉深度,从而尽量减少肌肉松弛剂的使用。由于可通过测定呼气末药物浓度来控制麻醉深度,挥发性吸入麻醉与其他麻醉方案相比,知晓发生率可能较低。

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