Maquiera E, Yañez S, Fernández L, Rodríguez F, Picáns I, Sánchez I, Jeréz J
Section of Allergy, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Allergol Immunopathol (Madr). 1996 Mar-Apr;24(2):87-8.
We describe a case of infectious mononucleosis-like as a manifestation of carbamazepine-induced anticonvulsant hypersensitivity syndrome. Patch testing to carbamazepine and phenytoin were positive and negative to phenobarbital. Our results suggest a cell mediated type of immune response in the pathogenesis of this syndrome. Patch testing may be helpful in the diagnosis of anticonvulsant hypersensitivity syndrome caused by carbamazepine.
我们描述了一例以传染性单核细胞增多症样表现为卡马西平诱导的抗惊厥药物超敏反应综合征。对卡马西平和苯妥英的斑贴试验呈阳性,而对苯巴比妥呈阴性。我们的结果提示在该综合征的发病机制中存在细胞介导的免疫反应类型。斑贴试验可能有助于诊断由卡马西平引起的抗惊厥药物超敏反应综合征。